Health

FDA reviewer recommends against Pfizer drug

A U.S. Food and Drug Administration medical reviewer recommended the agency not approve tafamidis, a drug developed by a Pfizer Inc. subsidiary to treat a rare genetic disorder that affects the nervous system. The reviewer said there was “inadequate” evidence the drug works, according to the Wall Street Journal.

This is the second recent setback for Pfizer. Last week, the New England Journal of Medicine published a study that found the pharmaceutical giant’s popular antibiotic azithromycin, sold under the brand name continue reading...

Pradaxa more dangerous than alternative

A study recently presented to the 2012 Thombosis and Hemostasis Summit of North America compared Pradaxa to Coumadin and found that Pradaxa has a higher risk of bleeding and other complications.

Manufacturer Boehringer Ingelheim Pharma markets Pradaxa as a preferable alternative to warfarin, because Pradaxa, despite these risks, doesn’t require frequent blood tests.

The two blood thinners are known by their chemical names warfarin, sold under brand name Coumadin, and dabigatran, ...

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Women underrepresented in clinical trials

An article in Canadian news magazine Maclean’s spotlights the fact that much medical and scientific research excludes female test subjects, leaving a sizable and potentially dangerous gap in clinical knowledge as to how a given medication or treatment may affect women.

The article mentions that a number of conditions, such as heart disease, appear to affect men and women differently in terms of frequency, symptoms or both. Yet men make up ...

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FDA says azithromycin increases risk of heart death

The U.S. Food and Drug Administration has notified healthcare professionals of a study published in the New England Journal of Medicine that found patients taking a widely used antibiotic are at higher risk for potentially deadly heart problems.

The study concerns Zithromax, the brand name for azithromycin, which is commonly prescribed for pneumonia and other common infections. The FDA announcement emphasizes that patients taking the drug shouldn’t stop without talking to their doctors.

According to the FDA announcement, azithromycin belongs to a ...

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Psychologist believes antidepressants overprescribed

In an interview with Ohio newspaper The Plain Dealer, psychologist Eric Maisel, author of “Rethinking Depression,” questions whether antidepressants are overprescribed.

Maisel points out that all diagnoses of depression are based on self-reporting. He questions whether much of what many medical providers now diagnose as depression requiring medication is, in fact, a natural reaction to some of life’s inevitable disappointments and losses.

In an introduction to the interview, Plain Dealer medical writer ...

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Popular “Z-Pack” antibiotic Zithromax doubles risk of death

A study published in the New England Journal of Medicine found that the popular antibiotic Zithromax caries a small but significant risk of sudden death from heart problems. Patients who took a five-day course were more than twice as likely to die than people taking different antibiotics. This risk was even higher for people who already had cardiovascular disease.

Zithromax is the brand name for azithromycin, which is used to treat common infections such as bronchitis and pneumonia. Its popularity is ...

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