Posts Tagged 'sglt2 inhibitors'

Case Report Highlights Diabetic Ketoacidosis Risk with SGLT2 Inhibitors

Another case report links sodium-glucose co-transporter 2 (SGLT2) inhibitors like Invokana to diabetic ketoacidosis, a severe and potentially fatal condition wherein the body produces too many blood acids. The article, published in the journal Practical Diabetes, presents the case of a 58-year-old woman who suffered severe diabetic ketoacidosis after her twice-daily insulin regimen was replaced by dapagliflozin.

SGLT2 inhibitors, the new class of type 2 diabetes medication introduce in 2013, were first linked to ...

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First Study on SGLT2 Inhibitor Use in Type 1 Diabetics Shows Increased Diabetic Ketoacidosis

sglt2 inhibitor results fall shortAccording to a Medscape article, the results of the first-ever Phase 2 study of sodium-glucose cotransporter-2 (SGLT2) inhibitor use in type 1 diabetes patients have been reported—and they may not be as reassuring as many had hoped. The data were presented at the European Association for the Study of Diabetes (EASD) 2015 Meeting by Robert R. Henry, MD, chief of the Division of Endocrinology and Metabolism at the University ...

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FDA Updates SGLT2 Inhibitor Labels, Strengthens Bone Fracture Warnings

sglt2 inhibitors get stronger warnings regarding bone fracturesThe U.S. Food and Drug Administration (FDA) has released a safety alert for Invokana and Invokamet, two drugs in a new line of diabetes medications called sodium-glucose cotransporter-2 (SGLT2) inhibitors. The agency has strengthened warnings about the increased risk of bone fractures associated with the drugs and added information about loss of bone mineral density. Both Invokana (canaglifolozin) and Invokamet (canagliflozin and metformin) use Janssen Pharmaceutical’s SGLT2 inhibitor ...

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New SGLT2 Inhibitor Joins Troubled Class of Diabetes Drugs

new sglt2 inhibitor set to go to marketAccording to a Nasdaq report, the U.S. Food and Drug Administration (FDA) has approved Eli Lilly and Boehringer Ingelheim’s new type 2 diabetes drug, Synjardy. Synjardy is the latest in a new line of diabetes medications known as sodium-glucose cotransporter-2 inhibitors, called SGLT2 inhibitors for short.

SGLT2 inhibitors help lower patients’ blood sugar by preventing reabsorption of glucose in the kidneys and eliminating excess sugar through ...

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Diabetic Ketoacidosis Connection Remains despite SGLT2 Inhibitor Trial Results

A recent Reuters article reports that Eli Lilly & Co. and Boehringer Ingelheim have received positive results for their sodium-glucose cotransporter-2 (SGLT2) inhibitor Jardiance. According to a recent drug trial, empagliflozin (Jardiance) can cut patients’ risk of cardiovascular problems like heart attack and stroke. But Jardiance and other SGLT2 inhibitors still cannot seem to escape the shadow of diabetic ketoacidosis, a potentially fatal blood condition to which the new class of diabetes drugs ...

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New Thoughts on SGLT2 Inhibitor–Induced Diabetic Ketoacidosis

questions remain about sglt2 inhibitorsWhile sodium-glucose cotransporter-2 (SGLT2) inhibitors draw praise for their weight-loss and blood pressure reduction benefits, medical experts continue to puzzle over their more immediate metabolic and immune system effects. Specifically, researchers are worried about their possible link to diabetic ketoacidosis, a potentially fatal condition caused by excess blood acids, or ketones. In an article published by the Journal of Diabetes Investigation, two Japanese researchers provide a possible explanation for how continue reading...

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